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Home > Treatments > Blood Purification >

Blood Purification

The wastes and toxins lodging in the kidneys are the biggest obstacle for the treatment of kidney diseases. Blood Purification combines with different types of blood purification techniques to clear out the wastes and toxins in patients’ body.

What is Blood Purification?

Blood purification is applied to eliminate all kinds of blood stasis through filtration with the help of advanced techniques and equipments so as to remove waste, toxin and metabolite out of body. The common types of blood purification include hemodialysis, hemofiltration, hemoperfusion, immune adsorption, plasma exchange and CRRT.

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What are methods and functions of Blood Purification?

Hemodialysis:

Hemodialysis aims at clearing blood stasis of small molecule in blood flow, which is the most common way to treat advanced and permanent kidney failure by carrying on an active life despite failing kidneys. Hemodialysis is a serious responsibility that your healthcare team will work closely with you, which includes expert kidney specialist and other professionals.

-Get rid of small sized blood stasis, such as urea, creatinine, BUN, etc.

-Remove excess water out of body.

-Maintain the balance of electrolytes in the blood.

Hemofiltration:

Hemofiltration is a therapy similar to hemodialysis, which is use to replace the function of kidneys in the case of kidney failure. Compared with hemodialysis, hemofiltration is always used in intensive care settings in case of acute renal failure.

-Remove the small and middle sized wastes in the blood, like chemicals, bilirubin and excessive vitamins.

-Eliminate a few of large sized toxins in the blood, such as cytokines and inflammatory mediators.

-Control the inflammations.

Hemoperfusion:

This treatment technique aims at passing over large volumes of blood through an adsorbent substance so as to eliminate toxic substances out of blood flow. It is sometimes described as an extracorporeal form of treatment because the blood is pumped through a device which is outside the body.

-Eliminate nephrotoxic drugs or poisons from the blood in emergency situations.

-Remove waste products from the blood in patients with CKD.

-Compared with other treatment, it is more effective in removing some specific wastes out of the blood, especially those bind to proteins in the body.

Immune adsorption:

Immune adsorption is a therapy which uses adsorbing materials to alternatively or specifically remove the pathogenic factors related to immune system in the blood. It usually used in immune system diseases and liver diseases.

-Remove the large-molecule toxins in the blood, such as immunoglobulin, immune complexes, albumin, endotoxin, cytokines and inflammatory mediators.

-Remove antigen by specific antiserum in a similar manner.

-Remove the antibody from antiserum by use of specific antigen.

-Taking effect quickly.

Plasma exchange:

Plasmapheresis is done to exchange plasma in the blood. Plasma is the liquid part of the blood that does not contain cells. Once the plasma is removed, fresh plasma or a plasma substitute is added back to the blood.

It shows promising effects in treating the following kidney diseases: anti-glomerular basement membrane disease, Acute Glomerulonephritis, serious Focal Segmental Glomerulonephritis, Lupus Nephritis, crescent Glomerulonephritis, immune kidney disease, lipoprotein glomerulopathy etc.

CRRT:

CRRT, Continuous Renal Replacement Therapy as its full name, is designed to provide artificial kidney support to patients who could not tolerate traditional hemodialysis. CRRT is intended to run for 24 hours a day, but the average therapy time is actually closer to 16 hours a day due to interruption. It deals with all sized waste molecules in the blood.

If your patient is critically ill with acute kidney injury (AKI), CRRT is one of the primary therapies. The goal of any continuous renal replacement therapy (CRRT) is to replace, as best as possible, the lost function of kidneys. CRRT provides slow and balanced fluid removal that even unstable patients - those with shock or severe fluid overload - can more easily tolerate. Both average and smaller size patients can undergo CRRT therapy and it can be adapted quickly to meet changing needs.

The key point of degradability is to degrade extracellular matrix, thus repairing renal injuries and restoring renal functions efficiently and sufficiently.

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