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Home > Diseases and Conditions > End Stage Renal Disease > End Stage Renal Disease Basics >

How High Does Creatinine To Be for End Stage Renal Failure

How High Does Creatinine To Be for End Stage Renal FailureWhen it comes to kidney problem, creatinine level is a concern, because serum creatinine level increases with the decline of kidney function. Well, how high does creatinine to be for End Stage Renal Failure?

End Stage Renal Failure is also commonly called ESRD (End Stage Renal Disease) which refers to the worst kidney condition. In such a case, kidneys have lost almost all its function and can not remove excess creatinine out of the body any more. So creatinine level is usually very high. Kidney works through about a million of nephrons. When a small number of nephrons are damaged, residual kidney function is powerful enough to maintain a normal serum creatinine level. According to clinical studies, when about a half of kidney function is impaired, creatinine level in blood begins to go up.

Normally, serum creatinine level stays in the range of 0.5-1.3mg/dL. Creatinine level in blood reflects kidney function, but there is no such a number that explicitly indicates End Stage Renal Failure, because creatinine level in ESRD differs from case to case. Even though there is no a clear number, but generally, serum creatinine level is higher than 4 when illness develops to end stage.

Besides, serum creatinine level is just one of the indicators of kidney function. Apart from it, GFR(Glomerular Filtration Rate) also can be used to measure kidney condition. Chronic kidney problem is divided into 5 stages according to GFR. We say illness is in end stage, when GFR is lower than 15.

Both serum creatinine level and GFR can b applied to learn about kidney function. In general, the lower the GFR, the higher the serum creatinine level. End Stage Renal Failure is the last stage of all kinds of kidney problem. If we want to prevent it, we need to take treatment as soon as possible to keep illness in early stage.

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